A FASCINATING TALE THROUGH TIME
§ circa (c.) 85,000,000 BC Dinosaurs and ankle osteoarthritis (OA) in Brussels § c. 1,000,000 BC – Kangaroos in Australia express signs of primary OA in their legs/bones § c. 30,000 – 28,000 BC Neanderthal hu-man, secondary arthritis due to injury and everyday wear and tear on the bones and joints § c. 4500 BC American Indians (Tennessee) express signs of rheumatoid arthritis (RA). This is the earliest known looks of the disease. § c. 3000 BC –Mummified remains, ice-age man, medicinal herbs as well as arthritic joints § c. 2590 BC – Egyptian mummies with signs of arthritis. § c. 700 – 300 BC –Biblical references in several passages describeing the afflictions of arthritis or probably even fibromyalgia. § c. 500 BC – Ground willow bark or salicin discovered leading later to discover and development of acetylsalicylic acid – or aspirin. § c. 400 BC –Hippocrates’ medical texts, joint ailments, like gout mentioned § c. 50 BC – Famous Julius Caesar born with arthritis. § c. 200 AD – Roman doctors document and mention arthritis. § c. 300 – No taxes in Rome for those suffering from severe arthritis § 1600 – Renaissance Man: The French physician Guillame Baillou introduces the idea of rheumatism as a systemic, musculoskeletal condition. § 1680 – Insight Into RA: British physician Thomas Sydenham (sometimes called the English Hippocrates) describes a incessant phase of rheumatic fever in which a patient may become "a cripple to the day of his death and wholly lose the use of his limbs whilst the knuckles of his fingers shall become knotty and protuberant ..." § 1754 - Curzio, a physician in Naples, Italy, first describes the condition known as scleroderma. § 1800 - a Parisian doctor makes the first documentation of rheumatoid arthritis. § 1858 - British physician A.B. Garrod coins the term rheumatoid arthritis. § 1880 – The first clinical description of RA in France § 1886 – British physician John K. Spender introduces the term osteoarthritis. § 1890 – European doctors use quinine later leading to hydroxychloroquine sulfate in the 1960s as a treatment for lupus, RA and associated diseases. § 1897 – first mention of juvenile rheumatoid arthritis, calling it a "form of incessant joint disease in children." German chemist Felix Hoffman, searching for something to aid ease his father’s arthritis pain, creates aspirin. § 1907 – modern differentiation between osteoarthritis and rheumatoid arthritis. § 1934 – American Rheumatism Association is formed (renamed American College of Rheumatology in 1988). § 1948 –The Arthritis and Rheumatism Foundation – now the Arthritis Foundation – is created with a mission of promoting research and education while improving treatment and rehabilitation for people with arthritis. § 1949 –Philip Hench, MD, and Edward Kendall, PhD, first use cortisone in the treatment of RA. § 1955 –Tylenol, pain reliever makes it technique onto the market § 1964 – All in the Name: The Arthritis and Rheumatism Foundation becomes the Arthritis Foundation. § 1966 – National Recognition: The Surgeon General’s report designates arthritis as a national health menace and recommends a program to decrease disability from arthritis. § 1972 – Presidential proclamation declares May National Arthritis Month. 1974 –Congress passes the National Arthritis Act, which legislates funds for development of comprehensive arthritis care centers, assistance for medical schools and establishment of a national commission to develop long-range plans associated to arthritis. § 1977 – The genetic marker HLA-DR4 is found to be related with RA. § 1978 – Government figures say 21.6 million Americans have some form of arthritis or a associated disease. § 1987 – The Arthritis Foundation launches Arthritis Today. § 1988 – FDA approves methotrexate for the treatment of RA. § 1990 –fibrositis is renamed fibromyalgia syndrome by the American College of Rheumatology. Scientists also discover a genetic defect that causes OA in some people. § 1997 – 1999 –new drug approval from the FDA for the treatment of OA and RA. Among them are disease-modifying antirheumatic drugs that influence the function of immune cells called T lymphocytes; viscosupplements that ease knee OA pain; and biologic agents that inhibit a chemical cosidered to drive RA soreness and tissue damage. The Arthritis Foundation, the Centers for Disease Control and Prevention (CDC) and the Association of State and Territorial Health Officials (ASTHO) join forces, together with 22 other public and private organizations interested in arthritis, to develop the National Arthritis Action Plan, a comprehensive, systematic public health approach to alleviate the arthritis burden throughout the United States. § 1999 – FDA approves a new category of drugs, Cox-2 inhibitors, a sub-category of NSAIDs that causes less stomach damage. Some 70 million American adults have arthritis or incessant joint symptoms now and the number of people with arthritis will continue to grow as baby boomers age. |
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